This gene encodes a member of the nucleosome assembly protein (NAP) family which can interact with both core and linker histones. It can shuttle between the cytoplasm and nucleus, suggesting a role as a histone chaperone. This gene is one of several located near the imprinted gene domain of 11p15.5, an important tumor-suppressor gene region. Alterations in this region have been associated with the Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocortical carcinoma, and lung, ovarian, and breast cancer. [provided by RefSeq, Jul 2008]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| NAP1L4-20-RE | 20 (40 μL) | 200 μL |  |
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| NAP1L4-20-OR | 20 (40 μL) | 200 μL |  |
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| NAP1L4-20-GO | 20 (40 μL) | 200 μL |  |
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| NAP1L4-20-GR | 20 (40 μL) | 200 μL |  |
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| NAP1L4-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene encodes a member of the nucleosome assembly protein (NAP) family which can interact with both core and linker histones. It can shuttle between the cytoplasm and nucleus, suggesting a role as a histone chaperone. This gene is one of several located near the imprinted gene domain of 11p15.5, an important tumor-suppressor gene region. Alterations in this region have been associated with the Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocortical carcinoma, and lung, ovarian, and breast cancer. [provided by RefSeq, Jul 2008]
Gene Symbol : NAP1L4
Gene Name : Nucleosome assembly protein 1 like 4
Chromosome : CHR 11: 299,237,6-294,442,9
Locus : 11p15.4
Alt. Genes : CLEC3A
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