This gene encodes a member of the peptidase A1 family of aspartic proteases. The encoded preproprotein is proteolytically processed to generate an activation peptide and the mature protease. The activation peptides of aspartic proteinases function as inhibitors of the protease active site. These peptide segments, or pro-parts, are deemed important for correct folding, targeting, and control of the activation of aspartic proteinase zymogens. The encoded protease may play a role in the proteolytic processing of pulmonary surfactant protein B in the lung and may function in protein catabolism in the renal proximal tubules. This gene has been described as a marker for lung adenocarcinoma and renal cell carcinoma. [provided by RefSeq, Feb 2016]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| NAPSA-20-RE | 20 (40 μL) | 200 μL |  |
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| NAPSA-20-OR | 20 (40 μL) | 200 μL |  |
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| NAPSA-20-GO | 20 (40 μL) | 200 μL |  |
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| NAPSA-20-GR | 20 (40 μL) | 200 μL |  |
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| NAPSA-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene encodes a member of the peptidase A1 family of aspartic proteases. The encoded preproprotein is proteolytically processed to generate an activation peptide and the mature protease. The activation peptides of aspartic proteinases function as inhibitors of the protease active site. These peptide segments, or pro-parts, are deemed important for correct folding, targeting, and control of the activation of aspartic proteinase zymogens. The encoded protease may play a role in the proteolytic processing of pulmonary surfactant protein B in the lung and may function in protein catabolism in the renal proximal tubules. This gene has been described as a marker for lung adenocarcinoma and renal cell carcinoma. [provided by RefSeq, Feb 2016]
Gene Symbol : NAPSA
Gene Name : Napsin A aspartic peptidase
Chromosome : CHR 19: 503,693,30-503,584,71
Locus : 19q13.33
Alt. Genes : MPHOSPH9
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