This gene product is the founding member of the evolutionarily conserved CAN (Cerberus and DAN) family of proteins, which contain a domain resembling the CTCK (C-terminal cystine knot-like) motif found in a number of signaling molecules. These proteins are secreted, and act as BMP (bone morphogenetic protein) antagonists by binding to BMPs and preventing them from interacting with their receptors. They may thus play an important role during growth and development. Alternatively spliced transcript variants have been identified for this gene. Read-through transcripts between this locus and the upstream mitochondrial inner membrane organizing system 1 gene (GeneID 440574) have been observed. [provided by RefSeq, May 2013]
SKU | Test Kits | Buffer | Dye Color | Order Now |
---|---|---|---|---|
NBL1-20-RE | 20 (40 μL) | 200 μL | Request Pricing | |
NBL1-20-OR | 20 (40 μL) | 200 μL | Request Pricing | |
NBL1-20-GO | 20 (40 μL) | 200 μL | Request Pricing | |
NBL1-20-GR | 20 (40 μL) | 200 μL | Request Pricing | |
NBL1-20-AQ | 20 (40 μL) | 200 μL | Request Pricing |
This gene product is the founding member of the evolutionarily conserved CAN (Cerberus and DAN) family of proteins, which contain a domain resembling the CTCK (C-terminal cystine knot-like) motif found in a number of signaling molecules. These proteins are secreted, and act as BMP (bone morphogenetic protein) antagonists by binding to BMPs and preventing them from interacting with their receptors. They may thus play an important role during growth and development. Alternatively spliced transcript variants have been identified for this gene. Read-through transcripts between this locus and the upstream mitochondrial inner membrane organizing system 1 gene (GeneID 440574) have been observed. [provided by RefSeq, May 2013]
Gene Symbol : NBL1
Gene Name : Neuroblastoma 1, DAN family BMP antagonist
Chromosome : CHR 1: 196,432,28-196,584,55
Locus : 1p36.13
Alt. Genes : DHRS9
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