The protein encoded by this gene was originally identified as an ovarian tumor antigen monitored in ovarian cancer. The encoded protein contains a B-box/coiled-coil motif, which is present in many genes with transformation potential. It functions as a specific autophagy receptor for the selective autophagic degradation of peroxisomes by forming intracellular inclusions with ubiquitylated autophagic substrates. This gene is located on a region of chromosome 17q21.1 that is in close proximity to the BRCA1 tumor suppressor gene. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Apr 2014]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| NBR1-20-RE | 20 (40 μL) | 200 μL |  |
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| NBR1-20-OR | 20 (40 μL) | 200 μL |  |
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| NBR1-20-GO | 20 (40 μL) | 200 μL |  |
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| NBR1-20-GR | 20 (40 μL) | 200 μL |  |
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| NBR1-20-AQ | 20 (40 μL) | 200 μL |  |
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The protein encoded by this gene was originally identified as an ovarian tumor antigen monitored in ovarian cancer. The encoded protein contains a B-box/coiled-coil motif, which is present in many genes with transformation potential. It functions as a specific autophagy receptor for the selective autophagic degradation of peroxisomes by forming intracellular inclusions with ubiquitylated autophagic substrates. This gene is located on a region of chromosome 17q21.1 that is in close proximity to the BRCA1 tumor suppressor gene. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Apr 2014]
Gene Symbol : NBR1
Gene Name : NBR1, autophagy cargo receptor
Chromosome : CHR 17: 431,704,70-432,116,88
Locus : 17q21.31
Alt. Genes : HIPK3
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