The product of this gene is a component of the nuclear cap-binding protein complex (CBC), which binds to the monomethylated 5' cap of nascent pre-mRNA in the nucleoplasm. The encoded protein promotes high-affinity mRNA-cap binding and associates with the CTD of RNA polymerase II. The CBC promotes pre-mRNA splicing, 3'-end processing, RNA nuclear export, and nonsense-mediated mRNA decay. [provided by RefSeq, Jul 2008]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| NCBP1-20-RE | 20 (40 μL) | 200 μL |  |
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| NCBP1-20-OR | 20 (40 μL) | 200 μL |  |
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| NCBP1-20-GO | 20 (40 μL) | 200 μL |  |
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| NCBP1-20-GR | 20 (40 μL) | 200 μL |  |
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| NCBP1-20-AQ | 20 (40 μL) | 200 μL |  |
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The product of this gene is a component of the nuclear cap-binding protein complex (CBC), which binds to the monomethylated 5' cap of nascent pre-mRNA in the nucleoplasm. The encoded protein promotes high-affinity mRNA-cap binding and associates with the CTD of RNA polymerase II. The CBC promotes pre-mRNA splicing, 3'-end processing, RNA nuclear export, and nonsense-mediated mRNA decay. [provided by RefSeq, Jul 2008]
Gene Symbol : NCBP1
Gene Name : Nuclear cap binding protein subunit 1
Chromosome : CHR 9: 976,334,22-976,737,47
Locus : 9q22.33
Alt. Genes : SGK2
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