This gene is a member of the N-myc downregulated gene family which belongs to the alpha/beta hydrolase superfamily. The protein encoded by this gene is a cytoplasmic protein involved in stress responses, hormone responses, cell growth, and differentiation. The encoded protein is necessary for p53-mediated caspase activation and apoptosis. Mutations in this gene are a cause of Charcot-Marie-Tooth disease type 4D, and expression of this gene may be a prognostic indicator for several types of cancer. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, May 2012]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| NDRG1-20-RE | 20 (40 μL) | 200 μL |  |
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| NDRG1-20-OR | 20 (40 μL) | 200 μL |  |
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| NDRG1-20-GO | 20 (40 μL) | 200 μL |  |
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| NDRG1-20-GR | 20 (40 μL) | 200 μL |  |
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| NDRG1-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene is a member of the N-myc downregulated gene family which belongs to the alpha/beta hydrolase superfamily. The protein encoded by this gene is a cytoplasmic protein involved in stress responses, hormone responses, cell growth, and differentiation. The encoded protein is necessary for p53-mediated caspase activation and apoptosis. Mutations in this gene are a cause of Charcot-Marie-Tooth disease type 4D, and expression of this gene may be a prognostic indicator for several types of cancer. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, May 2012]
Gene Symbol : NDRG1
Gene Name : N-myc downstream regulated 1
Chromosome : CHR 8: 133,297,586-133,237,170
Locus : 8q24.22
Alt. Genes : RBM12
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