This gene encodes an nuclear-encoded accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (complex I, or NADH:ubiquinone oxidoreductase). Complex I removes electrons from NADH and passes them to the electron acceptor ubiquinone. Mutations in this gene can cause mitochondrial complex I deficiencies such as Leigh syndrome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2015]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| NDUFS4-20-RE | 20 (40 μL) | 200 μL |  |
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| NDUFS4-20-OR | 20 (40 μL) | 200 μL |  |
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| NDUFS4-20-GO | 20 (40 μL) | 200 μL |  |
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| NDUFS4-20-GR | 20 (40 μL) | 200 μL |  |
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| NDUFS4-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene encodes an nuclear-encoded accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (complex I, or NADH:ubiquinone oxidoreductase). Complex I removes electrons from NADH and passes them to the electron acceptor ubiquinone. Mutations in this gene can cause mitochondrial complex I deficiencies such as Leigh syndrome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2015]
Gene Symbol : NDUFS4
Gene Name : NADH:ubiquinone oxidoreductase subunit S4
Chromosome : CHR 5: 535,606,09-536,833,40
Locus : 5q11.2
Alt. Genes : MKRN3-AS1
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