This gene encodes a subunit of mitochondrial NADH:ubiquinone oxidoreductase, or Complex I, a multimeric enzyme of the respiratory chain responsible for NADH oxidation, ubiquinone reduction, and the ejection of protons from mitochondria. The encoded protein is involved in the binding of two of the six to eight iron-sulfur clusters of Complex I and, as such, is required in the electron transfer process. Mutations in this gene have been associated with Leigh syndrome. [provided by RefSeq, Mar 2010]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| NDUFS8-20-RE | 20 (40 μL) | 200 μL |  |
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| NDUFS8-20-OR | 20 (40 μL) | 200 μL |  |
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| NDUFS8-20-GO | 20 (40 μL) | 200 μL |  |
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| NDUFS8-20-GR | 20 (40 μL) | 200 μL |  |
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| NDUFS8-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene encodes a subunit of mitochondrial NADH:ubiquinone oxidoreductase, or Complex I, a multimeric enzyme of the respiratory chain responsible for NADH oxidation, ubiquinone reduction, and the ejection of protons from mitochondria. The encoded protein is involved in the binding of two of the six to eight iron-sulfur clusters of Complex I and, as such, is required in the electron transfer process. Mutations in this gene have been associated with Leigh syndrome. [provided by RefSeq, Mar 2010]
Gene Symbol : NDUFS8
Gene Name : NADH:ubiquinone oxidoreductase core subunit S8
Chromosome : CHR 11: 680,306,16-680,366,46
Locus : 11q13.2
Alt. Genes : RBM12
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