Neurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and functionally maintain neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. This gene encodes the medium neurofilament protein. This protein is commonly used as a biomarker of neuronal damage. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Oct 2008]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| NEFM-20-RE | 20 (40 μL) | 200 μL |  |
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| NEFM-20-OR | 20 (40 μL) | 200 μL |  |
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| NEFM-20-GO | 20 (40 μL) | 200 μL |  |
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| NEFM-20-GR | 20 (40 μL) | 200 μL |  |
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| NEFM-20-AQ | 20 (40 μL) | 200 μL |  |
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Neurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and functionally maintain neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. This gene encodes the medium neurofilament protein. This protein is commonly used as a biomarker of neuronal damage. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Oct 2008]
Gene Symbol : NEFM
Gene Name : Neurofilament medium
Chromosome : CHR 8: 249,137,60-249,190,92
Locus : 8p21.2
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