The protein encoded by this gene is a serine/threonine protein kinase required for normal entry into replicative senescence. The encoded protein also is involved in cell cycle arrest in response to double-stranded DNA damage. Finally, this protein plays a role in maintaining cilium integrity, and defects in this gene have been associated with ciliopathies. [provided by RefSeq, Jan 2017]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| NEK4-20-RE | 20 (40 μL) | 200 μL |  |
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| NEK4-20-OR | 20 (40 μL) | 200 μL |  |
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| NEK4-20-GO | 20 (40 μL) | 200 μL |  |
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| NEK4-20-GR | 20 (40 μL) | 200 μL |  |
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| NEK4-20-AQ | 20 (40 μL) | 200 μL |  |
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The protein encoded by this gene is a serine/threonine protein kinase required for normal entry into replicative senescence. The encoded protein also is involved in cell cycle arrest in response to double-stranded DNA damage. Finally, this protein plays a role in maintaining cilium integrity, and defects in this gene have been associated with ciliopathies. [provided by RefSeq, Jan 2017]
Gene Symbol : NEK4
Gene Name : NIMA related kinase 4
Chromosome : CHR 3: 527,709,48-527,079,35
Locus : 3p21.1
Alt. Genes : LRPPRC
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