This gene is a member of the nuclear factor of activated T cells (NFAT) family. The product of this gene is a DNA-binding protein with a REL-homology region (RHR) and an NFAT-homology region (NHR). This protein is present in the cytosol and only translocates to the nucleus upon T cell receptor (TCR) stimulation, where it becomes a member of the nuclear factors of activated T cells transcription complex. This complex plays a central role in inducing gene transcription during the immune response. Alternate transcriptional splice variants encoding different isoforms have been characterized. [provided by RefSeq, Apr 2012]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| NFATC2-20-RE | 20 (40 μL) | 200 μL |  |
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| NFATC2-20-OR | 20 (40 μL) | 200 μL |  |
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| NFATC2-20-GO | 20 (40 μL) | 200 μL |  |
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| NFATC2-20-GR | 20 (40 μL) | 200 μL |  |
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| NFATC2-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene is a member of the nuclear factor of activated T cells (NFAT) family. The product of this gene is a DNA-binding protein with a REL-homology region (RHR) and an NFAT-homology region (NHR). This protein is present in the cytosol and only translocates to the nucleus upon T cell receptor (TCR) stimulation, where it becomes a member of the nuclear factors of activated T cells transcription complex. This complex plays a central role in inducing gene transcription during the immune response. Alternate transcriptional splice variants encoding different isoforms have been characterized. [provided by RefSeq, Apr 2012]
Gene Symbol : NFATC2
Gene Name : Nuclear factor of activated T-cells 2
Chromosome : CHR 20: 515,628,56-513,869,56
Locus : 20q13.2
Alt. Genes : PREB
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