This gene encodes a member of the nuclear factor of activated T cells (NFAT) protein family. The encoded protein is part of a DNA-binding transcription complex. This complex consists of at least two components: a preexisting cytosolic component that translocates to the nucleus upon T cell receptor stimulation and an inducible nuclear component. NFAT proteins are activated by the calmodulin-dependent phosphatase, calcineurin. The encoded protein plays a role in the inducible expression of cytokine genes in T cells, especially in the induction of interleukin-2 and interleukin-4. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| NFATC4-20-RE | 20 (40 μL) | 200 μL |  |
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| NFATC4-20-OR | 20 (40 μL) | 200 μL |  |
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| NFATC4-20-GO | 20 (40 μL) | 200 μL |  |
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| NFATC4-20-GR | 20 (40 μL) | 200 μL |  |
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| NFATC4-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene encodes a member of the nuclear factor of activated T cells (NFAT) protein family. The encoded protein is part of a DNA-binding transcription complex. This complex consists of at least two components: a preexisting cytosolic component that translocates to the nucleus upon T cell receptor stimulation and an inducible nuclear component. NFAT proteins are activated by the calmodulin-dependent phosphatase, calcineurin. The encoded protein plays a role in the inducible expression of cytokine genes in T cells, especially in the induction of interleukin-2 and interleukin-4. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014]
Gene Symbol : NFATC4
Gene Name : Nuclear factor of activated T-cells 4
Chromosome : CHR 14: 243,669,10-243,796,03
Locus : 14q12
Alt. Genes : RBM12
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