The protein encoded by this gene belongs to the NF-kappa-B inhibitor family, which inhibit NF-kappa-B by complexing with, and trapping it in the cytoplasm. Phosphorylation of serine residues on these proteins by kinases marks them for destruction via the ubiquitination pathway, thereby allowing activation of the NF-kappa-B, which translocates to the nucleus to function as a transcription factor. Alternatively spliced transcript variants have been found for this gene.[provided by RefSeq, Jul 2011]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| NFKBIB-20-RE | 20 (40 μL) | 200 μL |  |
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| NFKBIB-20-OR | 20 (40 μL) | 200 μL |  |
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| NFKBIB-20-GO | 20 (40 μL) | 200 μL |  |
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| NFKBIB-20-GR | 20 (40 μL) | 200 μL |  |
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| NFKBIB-20-AQ | 20 (40 μL) | 200 μL |  |
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The protein encoded by this gene belongs to the NF-kappa-B inhibitor family, which inhibit NF-kappa-B by complexing with, and trapping it in the cytoplasm. Phosphorylation of serine residues on these proteins by kinases marks them for destruction via the ubiquitination pathway, thereby allowing activation of the NF-kappa-B, which translocates to the nucleus to function as a transcription factor. Alternatively spliced transcript variants have been found for this gene.[provided by RefSeq, Jul 2011]
Gene Symbol : NFKBIB
Gene Name : NFKB inhibitor beta
Chromosome : CHR 19: 388,995,02-389,088,93
Locus : 19q13.2
Alt. Genes : RASA4
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