Iron-sulfur clusters are required for the function of many cellular enzymes. The proteins encoded by this gene supply inorganic sulfur to these clusters by removing the sulfur from cysteine, creating alanine in the process. This gene uses alternate in-frame translation initiation sites to generate mitochondrial forms and cytoplasmic/nuclear forms. Selection of the alternative initiation sites is determined by the cytosolic pH. The encoded proteins belong to the class-V family of pyridoxal phosphate-dependent aminotransferases. Alternatively spliced transcript variants have been described. [provided by RefSeq, Nov 2010]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| NFS1-20-RE | 20 (40 μL) | 200 μL |  |
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| NFS1-20-OR | 20 (40 μL) | 200 μL |  |
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| NFS1-20-GO | 20 (40 μL) | 200 μL |  |
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| NFS1-20-GR | 20 (40 μL) | 200 μL |  |
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| NFS1-20-AQ | 20 (40 μL) | 200 μL |  |
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Iron-sulfur clusters are required for the function of many cellular enzymes. The proteins encoded by this gene supply inorganic sulfur to these clusters by removing the sulfur from cysteine, creating alanine in the process. This gene uses alternate in-frame translation initiation sites to generate mitochondrial forms and cytoplasmic/nuclear forms. Selection of the alternative initiation sites is determined by the cytosolic pH. The encoded proteins belong to the class-V family of pyridoxal phosphate-dependent aminotransferases. Alternatively spliced transcript variants have been described. [provided by RefSeq, Nov 2010]
Gene Symbol : NFS1
Gene Name : NFS1, cysteine desulfurase
Chromosome : CHR 20: 356,993,64-356,686,87
Locus : 20q11.22
Alt. Genes : PREB
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