This gene encodes an enzyme that catalyzes hydrolysis of an N(4)-(acetyl-beta-D-glucosaminyl) asparagine residue to N-acetyl-beta-D-glucosaminylamine and a peptide containing an aspartate residue. The encoded enzyme may play a role in the proteasome-mediated degradation of misfolded glycoproteins. Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Feb 2009]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| NGLY1-20-RE | 20 (40 μL) | 200 μL |  |
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| NGLY1-20-OR | 20 (40 μL) | 200 μL |  |
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| NGLY1-20-GO | 20 (40 μL) | 200 μL |  |
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| NGLY1-20-GR | 20 (40 μL) | 200 μL |  |
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| NGLY1-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene encodes an enzyme that catalyzes hydrolysis of an N(4)-(acetyl-beta-D-glucosaminyl) asparagine residue to N-acetyl-beta-D-glucosaminylamine and a peptide containing an aspartate residue. The encoded enzyme may play a role in the proteasome-mediated degradation of misfolded glycoproteins. Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Feb 2009]
Gene Symbol : NGLY1
Gene Name : N-glycanase 1
Chromosome : CHR 3: 257,900,38-257,189,43
Locus : 3p24.2
Alt. Genes : MKRN3-AS1
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