Members of the NALP protein family typically contain a NACHT domain, a NACHT-associated domain (NAD), a C-terminal leucine-rich repeat (LRR) region, and an N-terminal pyrin domain (PYD). The protein encoded by this gene belongs to the NALP protein family despite lacking the LRR region. This protein likely plays a regulatory role in the innate immune system. The protein belongs to the signal-induced multiprotein complex, the inflammasome, that activates the pro-inflammatory caspases, caspase-1 and caspase-5. Other experiments indicate that this gene acts as a multifunctional negative regulator of inflammation and apoptosis. [provided by RefSeq, Jul 2008]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| NLRP10-20-RE | 20 (40 μL) | 200 μL |  |
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| NLRP10-20-OR | 20 (40 μL) | 200 μL |  |
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| NLRP10-20-GO | 20 (40 μL) | 200 μL |  |
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| NLRP10-20-GR | 20 (40 μL) | 200 μL |  |
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| NLRP10-20-AQ | 20 (40 μL) | 200 μL |  |
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Members of the NALP protein family typically contain a NACHT domain, a NACHT-associated domain (NAD), a C-terminal leucine-rich repeat (LRR) region, and an N-terminal pyrin domain (PYD). The protein encoded by this gene belongs to the NALP protein family despite lacking the LRR region. This protein likely plays a regulatory role in the innate immune system. The protein belongs to the signal-induced multiprotein complex, the inflammasome, that activates the pro-inflammatory caspases, caspase-1 and caspase-5. Other experiments indicate that this gene acts as a multifunctional negative regulator of inflammation and apoptosis. [provided by RefSeq, Jul 2008]
Gene Symbol : NLRP10
Gene Name : NLR family pyrin domain containing 10
Chromosome : CHR 11: 796,542,6-795,902,2
Locus : 11p15.4
Alt. Genes : LHFPL2
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