This gene is a member of the the NOD-like receptor protein (NLRP) gene family and encodes a protein with an N-terminal pyrin death (PYD) domain and nucleoside triphosphate hydrolase (NACHT) domain and a C-terminal leucine-rich repeats (LRR) region. This gene has been shown to regulate caspases in the proinflammatory signal transduction pathway and, based on studies of other members of the NLRP gene family with similar domain structure, is predicted to form part of the multiprotein inflammasome complex. Alternative splicing produces multiple transcript variants encoding distince isoforms. [provided by RefSeq, May 2017]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| NLRP11-20-RE | 20 (40 μL) | 200 μL |  |
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| NLRP11-20-OR | 20 (40 μL) | 200 μL |  |
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| NLRP11-20-GO | 20 (40 μL) | 200 μL |  |
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| NLRP11-20-GR | 20 (40 μL) | 200 μL |  |
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| NLRP11-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene is a member of the the NOD-like receptor protein (NLRP) gene family and encodes a protein with an N-terminal pyrin death (PYD) domain and nucleoside triphosphate hydrolase (NACHT) domain and a C-terminal leucine-rich repeats (LRR) region. This gene has been shown to regulate caspases in the proinflammatory signal transduction pathway and, based on studies of other members of the NLRP gene family with similar domain structure, is predicted to form part of the multiprotein inflammasome complex. Alternative splicing produces multiple transcript variants encoding distince isoforms. [provided by RefSeq, May 2017]
Gene Symbol : NLRP11
Gene Name : NLR family pyrin domain containing 11
Chromosome : CHR 19: 558,367,61-557,853,96
Locus : 19q13.42-q13.43
Alt. Genes : FST
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