This gene encodes a member of the NACHT, leucine rich repeat, and PYD containing (NLRP) protein family. It has an N-terminal pyrin domain, followed by a NACHT domain, a NACHT-associated domain (NAD), and a C-terminal leucine-rich repeat (LRR) region. NLRP proteins are implicated in the activation of proinflammatory caspases through multiprotein complexes called inflammasomes. This gene may act as a feedback regulator of caspase-1-dependent interleukin 1-beta secretion. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| NLRP7-20-RE | 20 (40 μL) | 200 μL |  |
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| NLRP7-20-OR | 20 (40 μL) | 200 μL |  |
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| NLRP7-20-GO | 20 (40 μL) | 200 μL |  |
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| NLRP7-20-GR | 20 (40 μL) | 200 μL |  |
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| NLRP7-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene encodes a member of the NACHT, leucine rich repeat, and PYD containing (NLRP) protein family. It has an N-terminal pyrin domain, followed by a NACHT domain, a NACHT-associated domain (NAD), and a C-terminal leucine-rich repeat (LRR) region. NLRP proteins are implicated in the activation of proinflammatory caspases through multiprotein complexes called inflammasomes. This gene may act as a feedback regulator of caspase-1-dependent interleukin 1-beta secretion. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
Gene Symbol : NLRP7
Gene Name : NLR family pyrin domain containing 7
Chromosome : CHR 19: 549,651,83-549,235,08
Locus : 19q13.42
Alt. Genes : SEMA4D
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