This gene encodes a 7-transmembrane G protein-coupled receptor that binds neuromedin B, which is a growth factor and mitogen for gastrointestinal epithelial tissue and for normal and neoplastic lung. This receptor may play a role in smooth muscle contraction, neuronal responses, and the regulation of cell growth. Antagonists of this receptor have a potential therapeutic use in inhibiting tumor cell growth. Polymorphisms in this gene may be associated with a susceptibility for schizophrenia. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Apr 2016]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| NMBR-20-RE | 20 (40 μL) | 200 μL |  |
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| NMBR-20-OR | 20 (40 μL) | 200 μL |  |
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| NMBR-20-GO | 20 (40 μL) | 200 μL |  |
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| NMBR-20-GR | 20 (40 μL) | 200 μL |  |
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| NMBR-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene encodes a 7-transmembrane G protein-coupled receptor that binds neuromedin B, which is a growth factor and mitogen for gastrointestinal epithelial tissue and for normal and neoplastic lung. This receptor may play a role in smooth muscle contraction, neuronal responses, and the regulation of cell growth. Antagonists of this receptor have a potential therapeutic use in inhibiting tumor cell growth. Polymorphisms in this gene may be associated with a susceptibility for schizophrenia. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Apr 2016]
Gene Symbol : NMBR
Gene Name : Neuromedin B receptor
Chromosome : CHR 6: 142,147,204-142,074,483
Locus : 6q24.1
Alt. Genes : LRPPRC
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