NPM1 FISH Probe

The protein encoded by this gene is involved in several cellular processes, including centrosome duplication, protein chaperoning, and cell proliferation. The encoded phosphoprotein shuttles between the nucleolus, nucleus, and cytoplasm, chaperoning ribosomal proteins and core histones from the nucleus to the cytoplasm. This protein is also known to sequester the tumor suppressor ARF in the nucleolus, protecting it from degradation until it is needed. Mutations in this gene are associated with acute myeloid leukemia. Dozens of pseudogenes of this gene have been identified. [provided by RefSeq, Aug 2017]


Gene Details
SKU Test Kits Buffer Dye Color Order Now
NPM1-20-RE 20 (40 μL) 200 μL color Request Pricing
NPM1-20-OR 20 (40 μL) 200 μL color Request Pricing
NPM1-20-GO 20 (40 μL) 200 μL color Request Pricing
NPM1-20-GR 20 (40 μL) 200 μL color Request Pricing
NPM1-20-AQ 20 (40 μL) 200 μL color Request Pricing

Gene Summary

The protein encoded by this gene is involved in several cellular processes, including centrosome duplication, protein chaperoning, and cell proliferation. The encoded phosphoprotein shuttles between the nucleolus, nucleus, and cytoplasm, chaperoning ribosomal proteins and core histones from the nucleus to the cytoplasm. This protein is also known to sequester the tumor suppressor ARF in the nucleolus, protecting it from degradation until it is needed. Mutations in this gene are associated with acute myeloid leukemia. Dozens of pseudogenes of this gene have been identified. [provided by RefSeq, Aug 2017]

Gene Details

Gene Symbol : NPM1

Gene Name : Nucleophosmin 1

Chromosome : CHR 5: 171,387,647-171,410,899

Locus : 5q35.1

Alt. Genes : AKAP9

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