This gene encodes a protein that contains a DNA-binding domain. The encoded protein acts as a dominant-negative regulator of transcription which is mediated by the retinoic acid receptor. This protein also functions as an anti-testis gene by acting antagonistically to Sry. Mutations in this gene result in both X-linked congenital adrenal hypoplasia and hypogonadotropic hypogonadism. [provided by RefSeq, Jul 2008]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| NR0B1-20-RE | 20 (40 μL) | 200 μL |  |
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| NR0B1-20-OR | 20 (40 μL) | 200 μL |  |
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| NR0B1-20-GO | 20 (40 μL) | 200 μL |  |
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| NR0B1-20-GR | 20 (40 μL) | 200 μL |  |
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| NR0B1-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene encodes a protein that contains a DNA-binding domain. The encoded protein acts as a dominant-negative regulator of transcription which is mediated by the retinoic acid receptor. This protein also functions as an anti-testis gene by acting antagonistically to Sry. Mutations in this gene result in both X-linked congenital adrenal hypoplasia and hypogonadotropic hypogonadism. [provided by RefSeq, Jul 2008]
Gene Symbol : NR0B1
Gene Name : Nuclear receptor subfamily 0 group B member 1
Chromosome : CHR X: 303,093,98-303,044,21
Locus : Xp21.2
Alt. Genes : ZNF263
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