This gene encodes a protein that belongs to the nuclear hormone receptor family. Members of this family act as ligand-activated transcription factors and function in many biological processes such as development, cellular differentiation and homeostasis. The activated receptor/ligand complex is translocated to the nucleus where it binds to hormone response elements of target genes. The protein encoded by this gene plays a role in protecting cells from oxidative stress and damage induced by ionizing radiation. The lack of a similar gene in mouse results in growth retardation, severe spinal curvature, subfertility, premature aging, and prostatic intraepithelial neoplasia (PIN) development. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Apr 2014]
SKU | Test Kits | Buffer | Dye Color | Order Now |
---|---|---|---|---|
NR2C2-20-RE | 20 (40 μL) | 200 μL | Request Pricing | |
NR2C2-20-OR | 20 (40 μL) | 200 μL | Request Pricing | |
NR2C2-20-GO | 20 (40 μL) | 200 μL | Request Pricing | |
NR2C2-20-GR | 20 (40 μL) | 200 μL | Request Pricing | |
NR2C2-20-AQ | 20 (40 μL) | 200 μL | Request Pricing |
This gene encodes a protein that belongs to the nuclear hormone receptor family. Members of this family act as ligand-activated transcription factors and function in many biological processes such as development, cellular differentiation and homeostasis. The activated receptor/ligand complex is translocated to the nucleus where it binds to hormone response elements of target genes. The protein encoded by this gene plays a role in protecting cells from oxidative stress and damage induced by ionizing radiation. The lack of a similar gene in mouse results in growth retardation, severe spinal curvature, subfertility, premature aging, and prostatic intraepithelial neoplasia (PIN) development. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Apr 2014]
Gene Symbol : NR2C2
Gene Name : Nuclear receptor subfamily 2 group C member 2
Chromosome : CHR 3: 149,475,83-150,492,78
Locus : 3p25.1
Alt. Genes : KIF20A
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