NRGN FISH Probe

Neurogranin (NRGN) is the human homolog of the neuron-specific rat RC3/neurogranin gene. This gene encodes a postsynaptic protein kinase substrate that binds calmodulin in the absence of calcium. The NRGN gene contains four exons and three introns. The exons 1 and 2 encode the protein and exons 3 and 4 contain untranslated sequences. It is suggested that the NRGN is a direct target for thyroid hormone in human brain, and that control of expression of this gene could underlay many of the consequences of hypothyroidism on mental states during development as well as in adult subjects. [provided by RefSeq, Jul 2008]


Gene Details
SKU Test Kits Buffer Dye Color Order Now
NRGN-20-RE 20 (40 μL) 200 μL color Request Pricing
NRGN-20-OR 20 (40 μL) 200 μL color Request Pricing
NRGN-20-GO 20 (40 μL) 200 μL color Request Pricing
NRGN-20-GR 20 (40 μL) 200 μL color Request Pricing
NRGN-20-AQ 20 (40 μL) 200 μL color Request Pricing

Gene Summary

Neurogranin (NRGN) is the human homolog of the neuron-specific rat RC3/neurogranin gene. This gene encodes a postsynaptic protein kinase substrate that binds calmodulin in the absence of calcium. The NRGN gene contains four exons and three introns. The exons 1 and 2 encode the protein and exons 3 and 4 contain untranslated sequences. It is suggested that the NRGN is a direct target for thyroid hormone in human brain, and that control of expression of this gene could underlay many of the consequences of hypothyroidism on mental states during development as well as in adult subjects. [provided by RefSeq, Jul 2008]

Gene Details

Gene Symbol : NRGN

Gene Name : Neurogranin

Chromosome : CHR 11: 124,739,932-124,747,205

Locus : 11q24.2

Alt. Genes : AASS

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