This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. The encoded preproprotein is proteolytically processed to generate the mature protein. This protein signals through the RET receptor tyrosine kinase and a GPI-linked coreceptor, and promotes survival of neuronal populations. A neurturin mutation has been described in a family with Hirschsprung Disease. [provided by RefSeq, Aug 2016]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| NRTN-20-RE | 20 (40 μL) | 200 μL |  |
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| NRTN-20-OR | 20 (40 μL) | 200 μL |  |
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| NRTN-20-GO | 20 (40 μL) | 200 μL |  |
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| NRTN-20-GR | 20 (40 μL) | 200 μL |  |
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| NRTN-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. The encoded preproprotein is proteolytically processed to generate the mature protein. This protein signals through the RET receptor tyrosine kinase and a GPI-linked coreceptor, and promotes survival of neuronal populations. A neurturin mutation has been described in a family with Hirschsprung Disease. [provided by RefSeq, Aug 2016]
Gene Symbol : NRTN
Gene Name : Neurturin
Chromosome : CHR 19: 580,538,6-582,832,3
Locus : 19p13.3
Alt. Genes : DHRS9
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