This gene encodes a protein with two coiled-coil domains that localizes to kinetochores, which are chromosome-associated structures that attach to microtubules and mediate chromosome movements during cell division. The encoded protein is part of a conserved protein complex that includes two chromodomain-containing proteins and a component of the outer plate of the kinetochore. This protein complex is proposed to bridge centromeric heterochromatin with the outer kinetochore structure. Multiple transcript variants encoding different isoforms have been found for this gene. There is a pseudogene of the 3' UTR region of this gene on chromosome X. [provided by RefSeq, Jul 2014]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| NSL1-20-RE | 20 (40 μL) | 200 μL |  |
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| NSL1-20-OR | 20 (40 μL) | 200 μL |  |
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| NSL1-20-GO | 20 (40 μL) | 200 μL |  |
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| NSL1-20-GR | 20 (40 μL) | 200 μL |  |
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| NSL1-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene encodes a protein with two coiled-coil domains that localizes to kinetochores, which are chromosome-associated structures that attach to microtubules and mediate chromosome movements during cell division. The encoded protein is part of a conserved protein complex that includes two chromodomain-containing proteins and a component of the outer plate of the kinetochore. This protein complex is proposed to bridge centromeric heterochromatin with the outer kinetochore structure. Multiple transcript variants encoding different isoforms have been found for this gene. There is a pseudogene of the 3' UTR region of this gene on chromosome X. [provided by RefSeq, Jul 2014]
Gene Symbol : NSL1
Gene Name : NSL1, MIS12 kinetochore complex component
Chromosome : CHR 1: 212,798,899-212,726,152
Locus : 1q32.3
Alt. Genes : ZNF263
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