This gene encodes a methyltransferase that catalyzes the methylation of cytosine to 5-methylcytosine (m5C) at position 34 of intron-containing tRNA(Leu)(CAA) precursors. This modification is necessary to stabilize the anticodon-codon pairing and correctly translate the mRNA. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.[provided by RefSeq, Mar 2011]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| NSUN2-20-RE | 20 (40 μL) | 200 μL |  |
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| NSUN2-20-OR | 20 (40 μL) | 200 μL |  |
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| NSUN2-20-GO | 20 (40 μL) | 200 μL |  |
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| NSUN2-20-GR | 20 (40 μL) | 200 μL |  |
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| NSUN2-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene encodes a methyltransferase that catalyzes the methylation of cytosine to 5-methylcytosine (m5C) at position 34 of intron-containing tRNA(Leu)(CAA) precursors. This modification is necessary to stabilize the anticodon-codon pairing and correctly translate the mRNA. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.[provided by RefSeq, Mar 2011]
Gene Symbol : NSUN2
Gene Name : NOP2/Sun RNA methyltransferase family member 2
Chromosome : CHR 5: 663,335,9-659,923,8
Locus : 5p15.31
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