This gene encodes a member of the neurotrophic tyrosine kinase receptor (NTKR) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. The presence of this kinase leads to cell differentiation and may play a role in specifying sensory neuron subtypes. Mutations in this gene have been associated with congenital insensitivity to pain, anhidrosis, self-mutilating behavior, cognitive disability and cancer. Alternate transcriptional splice variants of this gene have been found, but only three have been characterized to date. [provided by RefSeq, Jul 2008]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| NTRK1-20-RE | 20 (40 μL) | 200 μL |  |
Request Pricing |
| NTRK1-20-OR | 20 (40 μL) | 200 μL |  |
Request Pricing |
| NTRK1-20-GO | 20 (40 μL) | 200 μL |  |
Request Pricing |
| NTRK1-20-GR | 20 (40 μL) | 200 μL |  |
Request Pricing |
| NTRK1-20-AQ | 20 (40 μL) | 200 μL |  |
Request Pricing |
This gene encodes a member of the neurotrophic tyrosine kinase receptor (NTKR) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. The presence of this kinase leads to cell differentiation and may play a role in specifying sensory neuron subtypes. Mutations in this gene have been associated with congenital insensitivity to pain, anhidrosis, self-mutilating behavior, cognitive disability and cancer. Alternate transcriptional splice variants of this gene have been found, but only three have been characterized to date. [provided by RefSeq, Jul 2008]
Gene Symbol : NTRK1
Gene Name : Neurotrophic receptor tyrosine kinase 1
Chromosome : CHR 1: 156,815,749-156,881,849
Locus : 1q23.1
Alt. Genes : TRAP1
Lorem Ipsum is simply dummy text of the printing and typesetting industry.
Lorem Ipsum is simply dummy text of the printing and typesetting industry.