This gene encodes a protein that is highly similar to yeast Nuf2, a component of a conserved protein complex associated with the centromere. Yeast Nuf2 disappears from the centromere during meiotic prophase when centromeres lose their connection to the spindle pole body, and plays a regulatory role in chromosome segregation. The encoded protein is found to be associated with centromeres of mitotic HeLa cells, which suggests that this protein is a functional homolog of yeast Nuf2. Alternatively spliced transcript variants that encode the same protein have been described. [provided by RefSeq, Jul 2008]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| NUF2-20-RE | 20 (40 μL) | 200 μL |  |
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| NUF2-20-OR | 20 (40 μL) | 200 μL |  |
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| NUF2-20-GO | 20 (40 μL) | 200 μL |  |
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| NUF2-20-GR | 20 (40 μL) | 200 μL |  |
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| NUF2-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene encodes a protein that is highly similar to yeast Nuf2, a component of a conserved protein complex associated with the centromere. Yeast Nuf2 disappears from the centromere during meiotic prophase when centromeres lose their connection to the spindle pole body, and plays a regulatory role in chromosome segregation. The encoded protein is found to be associated with centromeres of mitotic HeLa cells, which suggests that this protein is a functional homolog of yeast Nuf2. Alternatively spliced transcript variants that encode the same protein have been described. [provided by RefSeq, Jul 2008]
Gene Symbol : NUF2
Gene Name : NUF2, NDC80 kinetochore complex component
Chromosome : CHR 1: 163,321,932-163,355,763
Locus : 1q23.3
Alt. Genes : PREB
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