This gene encodes a large protein that forms a structural component of the nuclear matrix. The encoded protein interacts with microtubules and plays a role in the formation and organization of the mitotic spindle during cell division. Chromosomal translocation of this gene with the RARA (retinoic acid receptor, alpha) gene on chromosome 17 have been detected in patients with acute promyelocytic leukemia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2013]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| NUMA1-20-RE | 20 (40 μL) | 200 μL |  |
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| NUMA1-20-OR | 20 (40 μL) | 200 μL |  |
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| NUMA1-20-GO | 20 (40 μL) | 200 μL |  |
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| NUMA1-20-GR | 20 (40 μL) | 200 μL |  |
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| NUMA1-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene encodes a large protein that forms a structural component of the nuclear matrix. The encoded protein interacts with microtubules and plays a role in the formation and organization of the mitotic spindle during cell division. Chromosomal translocation of this gene with the RARA (retinoic acid receptor, alpha) gene on chromosome 17 have been detected in patients with acute promyelocytic leukemia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2013]
Gene Symbol : NUMA1
Gene Name : Nuclear mitotic apparatus protein 1
Chromosome : CHR 11: 720,806,92-720,028,63
Locus : 11q13.4
Alt. Genes : ZNF263
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