The protein encoded by this gene plays a role in the determination of cell fates during development. The encoded protein, whose degradation is induced in a proteasome-dependent manner by MDM2, is a membrane-bound protein that has been shown to associate with EPS15, LNX1, and NOTCH1. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2016]
SKU | Test Kits | Buffer | Dye Color | Order Now |
---|---|---|---|---|
NUMB-20-RE | 20 (40 μL) | 200 μL | Request Pricing | |
NUMB-20-OR | 20 (40 μL) | 200 μL | Request Pricing | |
NUMB-20-GO | 20 (40 μL) | 200 μL | Request Pricing | |
NUMB-20-GR | 20 (40 μL) | 200 μL | Request Pricing | |
NUMB-20-AQ | 20 (40 μL) | 200 μL | Request Pricing |
The protein encoded by this gene plays a role in the determination of cell fates during development. The encoded protein, whose degradation is induced in a proteasome-dependent manner by MDM2, is a membrane-bound protein that has been shown to associate with EPS15, LNX1, and NOTCH1. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2016]
Gene Symbol : NUMB
Gene Name : NUMB, endocytic adaptor protein
Chromosome : CHR 14: 734,585,79-732,752,09
Locus : 14q24.2-q24.3
Alt. Genes : SGK2
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