This gene encodes an integral membrane protein that is required for cytokine-induced regulation of the tight junction paracellular permeability barrier. Mutations in this gene are thought to be a cause of band-like calcification with simplified gyration and polymicrogyria (BLC-PMG), an autosomal recessive neurologic disorder that is also known as pseudo-TORCH syndrome. Alternative splicing results in multiple transcript variants. A related pseudogene is present 1.5 Mb downstream on the q arm of chromosome 5. [provided by RefSeq, Apr 2011]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| OCLN-20-RE | 20 (40 μL) | 200 μL |  |
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| OCLN-20-OR | 20 (40 μL) | 200 μL |  |
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| OCLN-20-GO | 20 (40 μL) | 200 μL |  |
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| OCLN-20-GR | 20 (40 μL) | 200 μL |  |
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| OCLN-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene encodes an integral membrane protein that is required for cytokine-induced regulation of the tight junction paracellular permeability barrier. Mutations in this gene are thought to be a cause of band-like calcification with simplified gyration and polymicrogyria (BLC-PMG), an autosomal recessive neurologic disorder that is also known as pseudo-TORCH syndrome. Alternative splicing results in multiple transcript variants. A related pseudogene is present 1.5 Mb downstream on the q arm of chromosome 5. [provided by RefSeq, Apr 2011]
Gene Symbol : OCLN
Gene Name : Occludin
Chromosome : CHR 5: 694,922,91-695,581,03
Locus : 5q13.2
Alt. Genes : RBM12
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