This gene encodes a glycosyltransferase that catalyzes the addition of a single N-acetylglucosamine in O-glycosidic linkage to serine or threonine residues. Since both phosphorylation and glycosylation compete for similar serine or threonine residues, the two processes may compete for sites, or they may alter the substrate specificity of nearby sites by steric or electrostatic effects. The protein contains multiple tetratricopeptide repeats that are required for optimal recognition of substrates. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Oct 2009]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| OGT-20-RE | 20 (40 μL) | 200 μL |  |
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| OGT-20-OR | 20 (40 μL) | 200 μL |  |
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| OGT-20-GO | 20 (40 μL) | 200 μL |  |
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| OGT-20-GR | 20 (40 μL) | 200 μL |  |
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| OGT-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene encodes a glycosyltransferase that catalyzes the addition of a single N-acetylglucosamine in O-glycosidic linkage to serine or threonine residues. Since both phosphorylation and glycosylation compete for similar serine or threonine residues, the two processes may compete for sites, or they may alter the substrate specificity of nearby sites by steric or electrostatic effects. The protein contains multiple tetratricopeptide repeats that are required for optimal recognition of substrates. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Oct 2009]
Gene Symbol : OGT
Gene Name : O-linked N-acetylglucosamine (GlcNAc) transferase
Chromosome : CHR X: 715,330,61-715,758,96
Locus : Xq13.1
Alt. Genes : LRPPRC
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