This gene encodes a low density lipoprotein receptor that belongs to the C-type lectin superfamily. This gene is regulated through the cyclic AMP signaling pathway. The encoded protein binds, internalizes and degrades oxidized low-density lipoprotein. This protein may be involved in the regulation of Fas-induced apoptosis. This protein may play a role as a scavenger receptor. Mutations of this gene have been associated with atherosclerosis, risk of myocardial infarction, and may modify the risk of Alzheimer's disease. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Feb 2010]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| OLR1-20-RE | 20 (40 μL) | 200 μL |  |
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| OLR1-20-OR | 20 (40 μL) | 200 μL |  |
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| OLR1-20-GO | 20 (40 μL) | 200 μL |  |
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| OLR1-20-GR | 20 (40 μL) | 200 μL |  |
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| OLR1-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene encodes a low density lipoprotein receptor that belongs to the C-type lectin superfamily. This gene is regulated through the cyclic AMP signaling pathway. The encoded protein binds, internalizes and degrades oxidized low-density lipoprotein. This protein may be involved in the regulation of Fas-induced apoptosis. This protein may play a role as a scavenger receptor. Mutations of this gene have been associated with atherosclerosis, risk of myocardial infarction, and may modify the risk of Alzheimer's disease. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Feb 2010]
Gene Symbol : OLR1
Gene Name : Oxidized low density lipoprotein receptor 1
Chromosome : CHR 12: 101,721,90-101,582,99
Locus : 12p13.2
Alt. Genes : CHST4
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