The protein encoded by this gene is a membrane calcium channel subunit that is activated by the calcium sensor STIM1 when calcium stores are depleted. This type of channel is the primary way for calcium influx into T-cells. Defects in this gene are a cause of immune dysfunction with T-cell inactivation due to calcium entry defect type 1 (IDTICED1). [provided by RefSeq, Sep 2011]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| ORAI1-20-RE | 20 (40 μL) | 200 μL |  |
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| ORAI1-20-OR | 20 (40 μL) | 200 μL |  |
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| ORAI1-20-GO | 20 (40 μL) | 200 μL |  |
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| ORAI1-20-GR | 20 (40 μL) | 200 μL |  |
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| ORAI1-20-AQ | 20 (40 μL) | 200 μL |  |
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The protein encoded by this gene is a membrane calcium channel subunit that is activated by the calcium sensor STIM1 when calcium stores are depleted. This type of channel is the primary way for calcium influx into T-cells. Defects in this gene are a cause of immune dysfunction with T-cell inactivation due to calcium entry defect type 1 (IDTICED1). [provided by RefSeq, Sep 2011]
Gene Symbol : ORAI1
Gene Name : ORAI calcium release-activated calcium modulator 1
Chromosome : CHR 12: 121,626,549-121,642,039
Locus : 12q24.31
Alt. Genes : HIPK3
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