The origin recognition complex (ORC) is a highly conserved six subunit protein complex essential for the initiation of the DNA replication in eukaryotic cells. Studies in yeast demonstrated that ORC binds specifically to origins of replication and serves as a platform for the assembly of additional initiation factors such as Cdc6 and Mcm proteins. The protein encoded by this gene is a subunit of the ORC complex. Gene silencing studies with small interfering RNA demonstrated that this protein plays an essential role in coordinating chromosome replication and segregation with cytokinesis. [provided by RefSeq, Oct 2010]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| ORC6-20-RE | 20 (40 μL) | 200 μL |  |
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| ORC6-20-OR | 20 (40 μL) | 200 μL |  |
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| ORC6-20-GO | 20 (40 μL) | 200 μL |  |
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| ORC6-20-GR | 20 (40 μL) | 200 μL |  |
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| ORC6-20-AQ | 20 (40 μL) | 200 μL |  |
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The origin recognition complex (ORC) is a highly conserved six subunit protein complex essential for the initiation of the DNA replication in eukaryotic cells. Studies in yeast demonstrated that ORC binds specifically to origins of replication and serves as a platform for the assembly of additional initiation factors such as Cdc6 and Mcm proteins. The protein encoded by this gene is a subunit of the ORC complex. Gene silencing studies with small interfering RNA demonstrated that this protein plays an essential role in coordinating chromosome replication and segregation with cytokinesis. [provided by RefSeq, Oct 2010]
Gene Symbol : ORC6
Gene Name : Origin recognition complex subunit 6
Chromosome : CHR 16: 466,896,45-466,983,93
Locus : 16q11.2
Alt. Genes : RBM12
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