This gene encodes a member of the oxysterol-binding protein (OSBP) family, a group of intracellular lipid receptors. Most members contain an N-terminal pleckstrin homology domain and a highly conserved C-terminal OSBP-like sterol-binding domain, although the encoded protein contains only the sterol-binding domain. In vitro studies have shown that the encoded protein can bind strongly to phosphatic acid and weakly to phosphatidylinositol 3-phosphate, but cannot bind to 25-hydroxycholesterol. The protein associates with the Golgi apparatus. Transcript variants encoding different isoforms have been described. [provided by RefSeq, Sep 2014]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| OSBPL2-20-RE | 20 (40 μL) | 200 μL |  |
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| OSBPL2-20-OR | 20 (40 μL) | 200 μL |  |
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| OSBPL2-20-GO | 20 (40 μL) | 200 μL |  |
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| OSBPL2-20-GR | 20 (40 μL) | 200 μL |  |
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| OSBPL2-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene encodes a member of the oxysterol-binding protein (OSBP) family, a group of intracellular lipid receptors. Most members contain an N-terminal pleckstrin homology domain and a highly conserved C-terminal OSBP-like sterol-binding domain, although the encoded protein contains only the sterol-binding domain. In vitro studies have shown that the encoded protein can bind strongly to phosphatic acid and weakly to phosphatidylinositol 3-phosphate, but cannot bind to 25-hydroxycholesterol. The protein associates with the Golgi apparatus. Transcript variants encoding different isoforms have been described. [provided by RefSeq, Sep 2014]
Gene Symbol : OSBPL2
Gene Name : Oxysterol binding protein like 2
Chromosome : CHR 20: 622,384,84-622,962,12
Locus : 20q13.33
Alt. Genes : CEBPZ
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