This gene encodes a member of the type I cytokine receptor family. The encoded protein heterodimerizes with interleukin 6 signal transducer to form the type II oncostatin M receptor and with interleukin 31 receptor A to form the interleukin 31 receptor, and thus transduces oncostatin M and interleukin 31 induced signaling events. Mutations in this gene have been associated with familial primary localized cutaneous amyloidosis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2009]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| OSMR-20-RE | 20 (40 μL) | 200 μL |  |
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| OSMR-20-OR | 20 (40 μL) | 200 μL |  |
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| OSMR-20-GO | 20 (40 μL) | 200 μL |  |
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| OSMR-20-GR | 20 (40 μL) | 200 μL |  |
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| OSMR-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene encodes a member of the type I cytokine receptor family. The encoded protein heterodimerizes with interleukin 6 signal transducer to form the type II oncostatin M receptor and with interleukin 31 receptor A to form the interleukin 31 receptor, and thus transduces oncostatin M and interleukin 31 induced signaling events. Mutations in this gene have been associated with familial primary localized cutaneous amyloidosis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2009]
Gene Symbol : OSMR
Gene Name : Oncostatin M receptor
Chromosome : CHR 5: 388,458,57-389,455,78
Locus : 5p13.1
Alt. Genes : FAM13A
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