This gene encodes a G protein-coupled receptor (GPCR) that belongs to the oxoglutarate receptor family within the GPCR superfamily. The encoded protein is activated by the citric acid intermediate, oxoglutarate, as well as several cysteinyl leukotrienes, including leukotrienes E4, C4 and D4, which are implicated in many inflammatory disorders. In mice, a knock-out of this gene leads to middle ear inflammation, changes in the mucosal epithelium, and an increase in fluid behind the eardrum, and is associated with hearing loss. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2016]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| OXGR1-20-RE | 20 (40 μL) | 200 μL |  |
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| OXGR1-20-OR | 20 (40 μL) | 200 μL |  |
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| OXGR1-20-GO | 20 (40 μL) | 200 μL |  |
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| OXGR1-20-GR | 20 (40 μL) | 200 μL |  |
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| OXGR1-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene encodes a G protein-coupled receptor (GPCR) that belongs to the oxoglutarate receptor family within the GPCR superfamily. The encoded protein is activated by the citric acid intermediate, oxoglutarate, as well as several cysteinyl leukotrienes, including leukotrienes E4, C4 and D4, which are implicated in many inflammatory disorders. In mice, a knock-out of this gene leads to middle ear inflammation, changes in the mucosal epithelium, and an increase in fluid behind the eardrum, and is associated with hearing loss. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2016]
Gene Symbol : OXGR1
Gene Name : Oxoglutarate receptor 1
Chromosome : CHR 13: 969,958,41-969,857,18
Locus : 13q32.1
Alt. Genes : ATP6AP2
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