The protein encoded by this gene belongs to the family of P2X receptors, which are ATP-gated ion channels and mediate rapid and selective permeability to cations. This gene is predominantly expressed in skeletal muscle, and regulated by p53. The encoded protein is associated with VE-cadherin at the adherens junctions of human umbilical vein endothelial cells. Alternative splicing results in multiple transcript variants. A related pseudogene, which is also located on chromosome 22, has been identified. [provided by RefSeq, Apr 2009]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| P2RX6-20-RE | 20 (40 μL) | 200 μL |  |
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| P2RX6-20-OR | 20 (40 μL) | 200 μL |  |
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| P2RX6-20-GO | 20 (40 μL) | 200 μL |  |
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| P2RX6-20-GR | 20 (40 μL) | 200 μL |  |
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| P2RX6-20-AQ | 20 (40 μL) | 200 μL |  |
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The protein encoded by this gene belongs to the family of P2X receptors, which are ATP-gated ion channels and mediate rapid and selective permeability to cations. This gene is predominantly expressed in skeletal muscle, and regulated by p53. The encoded protein is associated with VE-cadherin at the adherens junctions of human umbilical vein endothelial cells. Alternative splicing results in multiple transcript variants. A related pseudogene, which is also located on chromosome 22, has been identified. [provided by RefSeq, Apr 2009]
Gene Symbol : P2RX6
Gene Name : Purinergic receptor P2X 6
Chromosome : CHR 22: 210,096,98-210,280,12
Locus : 22q11.21
Alt. Genes : CHST4
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