The product of this gene belongs to the family of purinoceptors for ATP. This receptor functions as a ligand-gated ion channel and is responsible for ATP-dependent lysis of macrophages through the formation of membrane pores permeable to large molecules. Activation of this nuclear receptor by ATP in the cytoplasm may be a mechanism by which cellular activity can be coupled to changes in gene expression. Multiple alternatively spliced variants have been identified, most of which fit nonsense-mediated decay (NMD) criteria. [provided by RefSeq, Jul 2010]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| P2RX7-20-RE | 20 (40 μL) | 200 μL |  |
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| P2RX7-20-OR | 20 (40 μL) | 200 μL |  |
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| P2RX7-20-GO | 20 (40 μL) | 200 μL |  |
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| P2RX7-20-GR | 20 (40 μL) | 200 μL |  |
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| P2RX7-20-AQ | 20 (40 μL) | 200 μL |  |
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The product of this gene belongs to the family of purinoceptors for ATP. This receptor functions as a ligand-gated ion channel and is responsible for ATP-dependent lysis of macrophages through the formation of membrane pores permeable to large molecules. Activation of this nuclear receptor by ATP in the cytoplasm may be a mechanism by which cellular activity can be coupled to changes in gene expression. Multiple alternatively spliced variants have been identified, most of which fit nonsense-mediated decay (NMD) criteria. [provided by RefSeq, Jul 2010]
Gene Symbol : P2RX7
Gene Name : Purinergic receptor P2X 7
Chromosome : CHR 12: 121,132,818-121,189,477
Locus : 12q24.31
Alt. Genes : CEBPZ
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