P4HA1 FISH Probe

This gene encodes a component of prolyl 4-hydroxylase, a key enzyme in collagen synthesis composed of two identical alpha subunits and two beta subunits. The encoded protein is one of several different types of alpha subunits and provides the major part of the catalytic site of the active enzyme. In collagen and related proteins, prolyl 4-hydroxylase catalyzes the formation of 4-hydroxyproline that is essential to the proper three-dimensional folding of newly synthesized procollagen chains. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008]


Gene Details
SKU Test Kits Buffer Dye Color Order Now
P4HA1-20-RE 20 (40 μL) 200 μL color Request Pricing
P4HA1-20-OR 20 (40 μL) 200 μL color Request Pricing
P4HA1-20-GO 20 (40 μL) 200 μL color Request Pricing
P4HA1-20-GR 20 (40 μL) 200 μL color Request Pricing
P4HA1-20-AQ 20 (40 μL) 200 μL color Request Pricing

Gene Summary

This gene encodes a component of prolyl 4-hydroxylase, a key enzyme in collagen synthesis composed of two identical alpha subunits and two beta subunits. The encoded protein is one of several different types of alpha subunits and provides the major part of the catalytic site of the active enzyme. In collagen and related proteins, prolyl 4-hydroxylase catalyzes the formation of 4-hydroxyproline that is essential to the proper three-dimensional folding of newly synthesized procollagen chains. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008]

Gene Details

Gene Symbol : P4HA1

Gene Name : Prolyl 4-hydroxylase subunit alpha 1

Chromosome : CHR 10: 730,969,73-730,072,16

Locus : 10q22.1

Alt. Genes : PREB

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