This gene encodes a poly(A) binding protein. The protein shuttles between the nucleus and cytoplasm and binds to the 3' poly(A) tail of eukaryotic messenger RNAs via RNA-recognition motifs. The binding of this protein to poly(A) promotes ribosome recruitment and translation initiation; it is also required for poly(A) shortening which is the first step in mRNA decay. The gene is part of a small gene family including three protein-coding genes and several pseudogenes.[provided by RefSeq, Aug 2010]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| PABPC1-20-RE | 20 (40 μL) | 200 μL |  |
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| PABPC1-20-OR | 20 (40 μL) | 200 μL |  |
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| PABPC1-20-GO | 20 (40 μL) | 200 μL |  |
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| PABPC1-20-GR | 20 (40 μL) | 200 μL |  |
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| PABPC1-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene encodes a poly(A) binding protein. The protein shuttles between the nucleus and cytoplasm and binds to the 3' poly(A) tail of eukaryotic messenger RNAs via RNA-recognition motifs. The binding of this protein to poly(A) promotes ribosome recruitment and translation initiation; it is also required for poly(A) shortening which is the first step in mRNA decay. The gene is part of a small gene family including three protein-coding genes and several pseudogenes.[provided by RefSeq, Aug 2010]
Gene Symbol : PABPC1
Gene Name : Poly(A) binding protein cytoplasmic 1
Chromosome : CHR 8: 100,722,997-100,702,915
Locus : 8q22.3
Alt. Genes : FEM1B
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