This gene encodes platelet-activating factor acetylhydrolase isoform 2, a single-subunit intracellular enzyme that catalyzes the removal of the acetyl group at the SN-2 position of platelet-activating factor (identified as 1-O-alkyl-2-acetyl-sn-glyceryl-3-phosphorylcholine). However, this lipase exhibits a broader substrate specificity than simply platelet activating factor. Two other isoforms of intracellular platelet-activating factor acetylhydrolase exist, and both are multi-subunit enzymes. Additionally, there is a single-subunit serum isoform of this enzyme. [provided by RefSeq, Jul 2008]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| PAFAH2-20-RE | 20 (40 μL) | 200 μL |  |
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| PAFAH2-20-OR | 20 (40 μL) | 200 μL |  |
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| PAFAH2-20-GO | 20 (40 μL) | 200 μL |  |
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| PAFAH2-20-GR | 20 (40 μL) | 200 μL |  |
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| PAFAH2-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene encodes platelet-activating factor acetylhydrolase isoform 2, a single-subunit intracellular enzyme that catalyzes the removal of the acetyl group at the SN-2 position of platelet-activating factor (identified as 1-O-alkyl-2-acetyl-sn-glyceryl-3-phosphorylcholine). However, this lipase exhibits a broader substrate specificity than simply platelet activating factor. Two other isoforms of intracellular platelet-activating factor acetylhydrolase exist, and both are multi-subunit enzymes. Additionally, there is a single-subunit serum isoform of this enzyme. [provided by RefSeq, Jul 2008]
Gene Symbol : PAFAH2
Gene Name : Platelet activating factor acetylhydrolase 2
Chromosome : CHR 1: 259,981,63-259,597,63
Locus : 1p36.11
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