Most mRNAs, except for histones, contain a 3-prime poly(A) tail. Poly(A)-binding protein (PABP; see MIM 604679) enhances translation by circularizing mRNA through its interaction with the translation initiation factor EIF4G1 (MIM 600495) and the poly(A) tail. Various PABP-binding proteins regulate PABP activity, including PAIP1 (MIM 605184), a translational stimulator, and PAIP2A (MIM 605604) and PAIP2B, translational inhibitors (Derry et al., 2006 [PubMed 17381337]).[supplied by OMIM, Mar 2008]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| PAIP2B-20-RE | 20 (40 μL) | 200 μL |  |
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| PAIP2B-20-OR | 20 (40 μL) | 200 μL |  |
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| PAIP2B-20-GO | 20 (40 μL) | 200 μL |  |
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| PAIP2B-20-GR | 20 (40 μL) | 200 μL |  |
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| PAIP2B-20-AQ | 20 (40 μL) | 200 μL |  |
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Most mRNAs, except for histones, contain a 3-prime poly(A) tail. Poly(A)-binding protein (PABP; see MIM 604679) enhances translation by circularizing mRNA through its interaction with the translation initiation factor EIF4G1 (MIM 600495) and the poly(A) tail. Various PABP-binding proteins regulate PABP activity, including PAIP1 (MIM 605184), a translational stimulator, and PAIP2A (MIM 605604) and PAIP2B, translational inhibitors (Derry et al., 2006 [PubMed 17381337]).[supplied by OMIM, Mar 2008]
Gene Symbol : PAIP2B
Gene Name : Poly(A) binding protein interacting protein 2B
Chromosome : CHR 2: 712,271,09-711,827,37
Locus : 2p13.3
Alt. Genes : LRPPRC
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