The p21 activated kinases (PAK) are critical effectors that link Rho GTPases to cytoskeleton reorganization and nuclear signaling. The PAK proteins are a family of serine/threonine kinases that serve as targets for the small GTP binding proteins, CDC42 and RAC1, and have been implicated in a wide range of biological activities. The protein encoded by this gene is activated by proteolytic cleavage during caspase-mediated apoptosis, and may play a role in regulating the apoptotic events in the dying cell. [provided by RefSeq, Jul 2008]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| PAK2-20-RE | 20 (40 μL) | 200 μL |  |
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| PAK2-20-OR | 20 (40 μL) | 200 μL |  |
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| PAK2-20-GO | 20 (40 μL) | 200 μL |  |
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| PAK2-20-GR | 20 (40 μL) | 200 μL |  |
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| PAK2-20-AQ | 20 (40 μL) | 200 μL |  |
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The p21 activated kinases (PAK) are critical effectors that link Rho GTPases to cytoskeleton reorganization and nuclear signaling. The PAK proteins are a family of serine/threonine kinases that serve as targets for the small GTP binding proteins, CDC42 and RAC1, and have been implicated in a wide range of biological activities. The protein encoded by this gene is activated by proteolytic cleavage during caspase-mediated apoptosis, and may play a role in regulating the apoptotic events in the dying cell. [provided by RefSeq, Jul 2008]
Gene Symbol : PAK2
Gene Name : P21 (RAC1) activated kinase 2
Chromosome : CHR 3: 196,739,856-196,832,646
Locus : 3q29
Alt. Genes : OPTN
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