Sulfation is a common modification of endogenous (lipids, proteins, and carbohydrates) and exogenous (xenobiotics and drugs) compounds. In mammals, the sulfate source is 3'-phosphoadenosine 5'-phosphosulfate (PAPS), created from ATP and inorganic sulfate. Two different tissue isoforms encoded by different genes synthesize PAPS. This gene encodes one of the two PAPS synthetases. Defects in this gene cause the Pakistani type of spondyloepimetaphyseal dysplasia. Two alternatively spliced transcript variants that encode different isoforms have been described for this gene. [provided by RefSeq, Jul 2008]
SKU | Test Kits | Buffer | Dye Color | Order Now |
---|---|---|---|---|
PAPSS2-20-RE | 20 (40 μL) | 200 μL | Request Pricing | |
PAPSS2-20-OR | 20 (40 μL) | 200 μL | Request Pricing | |
PAPSS2-20-GO | 20 (40 μL) | 200 μL | Request Pricing | |
PAPSS2-20-GR | 20 (40 μL) | 200 μL | Request Pricing | |
PAPSS2-20-AQ | 20 (40 μL) | 200 μL | Request Pricing |
Sulfation is a common modification of endogenous (lipids, proteins, and carbohydrates) and exogenous (xenobiotics and drugs) compounds. In mammals, the sulfate source is 3'-phosphoadenosine 5'-phosphosulfate (PAPS), created from ATP and inorganic sulfate. Two different tissue isoforms encoded by different genes synthesize PAPS. This gene encodes one of the two PAPS synthetases. Defects in this gene cause the Pakistani type of spondyloepimetaphyseal dysplasia. Two alternatively spliced transcript variants that encode different isoforms have been described for this gene. [provided by RefSeq, Jul 2008]
Gene Symbol : PAPSS2
Gene Name : 3'-phosphoadenosine 5'-phosphosulfate synthase 2
Chromosome : CHR 10: 876,597,18-877,477,04
Locus : 10q23.2-q23.31
Alt. Genes : OPTN
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Lorem Ipsum is simply dummy text of the printing and typesetting industry.