This gene is a member of the PAR6 family and encodes a protein with a PSD95/Discs-large/ZO1 (PDZ) domain and a semi-Cdc42/Rac interactive binding (CRIB) domain. This cell membrane protein is involved in asymmetrical cell division and cell polarization processes as a member of a multi-protein complex. The protein also has a role in the epithelial-to-mesenchymal transition (EMT) that characterizes the invasive phenotype associated with metastatic carcinomas. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| PARD6A-20-RE | 20 (40 μL) | 200 μL |  |
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| PARD6A-20-OR | 20 (40 μL) | 200 μL |  |
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| PARD6A-20-GO | 20 (40 μL) | 200 μL |  |
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| PARD6A-20-GR | 20 (40 μL) | 200 μL |  |
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| PARD6A-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene is a member of the PAR6 family and encodes a protein with a PSD95/Discs-large/ZO1 (PDZ) domain and a semi-Cdc42/Rac interactive binding (CRIB) domain. This cell membrane protein is involved in asymmetrical cell division and cell polarization processes as a member of a multi-protein complex. The protein also has a role in the epithelial-to-mesenchymal transition (EMT) that characterizes the invasive phenotype associated with metastatic carcinomas. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]
Gene Symbol : PARD6A
Gene Name : Par-6 family cell polarity regulator alpha
Chromosome : CHR 16: 676,609,47-676,627,77
Locus : 16q22.1
Alt. Genes : YAF2
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