This gene encodes poly(ADP-ribosyl)transferase-like 2 protein, which contains a catalytic domain and is capable of catalyzing a poly(ADP-ribosyl)ation reaction. This protein has a catalytic domain which is homologous to that of poly (ADP-ribosyl) transferase, but lacks an N-terminal DNA binding domain which activates the C-terminal catalytic domain of poly (ADP-ribosyl) transferase. The basic residues within the N-terminal region of this protein may bear potential DNA-binding properties, and may be involved in the nuclear and/or nucleolar targeting of the protein. Two alternatively spliced transcript variants encoding distinct isoforms have been found. [provided by RefSeq, Jul 2008]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| PARP2-20-RE | 20 (40 μL) | 200 μL |  |
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| PARP2-20-OR | 20 (40 μL) | 200 μL |  |
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| PARP2-20-GO | 20 (40 μL) | 200 μL |  |
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| PARP2-20-GR | 20 (40 μL) | 200 μL |  |
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| PARP2-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene encodes poly(ADP-ribosyl)transferase-like 2 protein, which contains a catalytic domain and is capable of catalyzing a poly(ADP-ribosyl)ation reaction. This protein has a catalytic domain which is homologous to that of poly (ADP-ribosyl) transferase, but lacks an N-terminal DNA binding domain which activates the C-terminal catalytic domain of poly (ADP-ribosyl) transferase. The basic residues within the N-terminal region of this protein may bear potential DNA-binding properties, and may be involved in the nuclear and/or nucleolar targeting of the protein. Two alternatively spliced transcript variants encoding distinct isoforms have been found. [provided by RefSeq, Jul 2008]
Gene Symbol : PARP2
Gene Name : Poly(ADP-ribose) polymerase 2
Chromosome : CHR 14: 203,430,40-203,579,03
Locus : 14q11.2
Alt. Genes : FEM1B
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