This gene encodes poly(ADP-ribosyl)transferase-like 1 protein, which is capable of catalyzing a poly(ADP-ribosyl)ation reaction. This protein has a catalytic domain which is homologous to that of poly (ADP-ribosyl) transferase, but lacks an N-terminal DNA binding domain which activates the C-terminal catalytic domain of poly (ADP-ribosyl) transferase. Since this protein is not capable of binding DNA directly, its transferase activity may be activated by other factors such as protein-protein interaction mediated by the extensive carboxyl terminus. [provided by RefSeq, Jul 2008]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| PARP4-20-RE | 20 (40 μL) | 200 μL |  |
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| PARP4-20-OR | 20 (40 μL) | 200 μL |  |
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| PARP4-20-GO | 20 (40 μL) | 200 μL |  |
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| PARP4-20-GR | 20 (40 μL) | 200 μL |  |
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| PARP4-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene encodes poly(ADP-ribosyl)transferase-like 1 protein, which is capable of catalyzing a poly(ADP-ribosyl)ation reaction. This protein has a catalytic domain which is homologous to that of poly (ADP-ribosyl) transferase, but lacks an N-terminal DNA binding domain which activates the C-terminal catalytic domain of poly (ADP-ribosyl) transferase. Since this protein is not capable of binding DNA directly, its transferase activity may be activated by other factors such as protein-protein interaction mediated by the extensive carboxyl terminus. [provided by RefSeq, Jul 2008]
Gene Symbol : PARP4
Gene Name : Poly(ADP-ribose) polymerase family member 4
Chromosome : CHR 13: 245,129,92-244,209,29
Locus : 13q12.12
Alt. Genes : SUGP2
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