This gene encodes a member of the parvin family of actin-binding proteins, which play a role in cytoskeleton organization and cell adhesion. These proteins are associated with focal contacts and contain calponin homology domains that bind to actin filaments. This family member binds to alphaPIX and alpha-actinin, and it can inhibit the activity of integrin-linked kinase. This protein also functions in tumor suppression. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Aug 2011]
SKU | Test Kits | Buffer | Dye Color | Order Now |
---|---|---|---|---|
PARVB-20-RE | 20 (40 μL) | 200 μL | Request Pricing | |
PARVB-20-OR | 20 (40 μL) | 200 μL | Request Pricing | |
PARVB-20-GO | 20 (40 μL) | 200 μL | Request Pricing | |
PARVB-20-GR | 20 (40 μL) | 200 μL | Request Pricing | |
PARVB-20-AQ | 20 (40 μL) | 200 μL | Request Pricing |
This gene encodes a member of the parvin family of actin-binding proteins, which play a role in cytoskeleton organization and cell adhesion. These proteins are associated with focal contacts and contain calponin homology domains that bind to actin filaments. This family member binds to alphaPIX and alpha-actinin, and it can inhibit the activity of integrin-linked kinase. This protein also functions in tumor suppression. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Aug 2011]
Gene Symbol : PARVB
Gene Name : Parvin beta
Chromosome : CHR 22: 439,992,10-441,692,32
Locus : 22q13.31
Alt. Genes : ZNF263
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